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A multicohort study published in The Lancet on Feb. 9/10, 2026 found that adults with obesity face markedly higher risks of hospitalisation or death from a wide range of infectious diseases.
Researchers pooled data from more than 540,000 participants in two Finnish cohorts and the UK Biobank, with an average follow-up of 13â14 years, and analysed associations across 925 bacterial, viral, parasitic and fungal infections.
People with a body-mass index (BMI) of 30 or higher had about a 70% greater risk of infection-related hospital admission or death compared with those with healthy BMI; the most severely obese had roughly threefold higher risk.
Using global mortality and obesity prevalence data, authors estimate obesity may account for about 11% (~600,000 of 5.4 million) of infection-related deaths in 2023, with country variation (about one in six in the UK and one in four in the US, versus ~1.2% in Vietnam). Associations persisted after accounting for chronic conditions; obesity did not appear to raise severe HIV or tuberculosis risk.
The study is observational and cannot prove causation; it was funded by Wellcome, the UK Medical Research Council and Finnish bodies.






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