A large observational study of 340,924 adults in the UK Biobank followed for about 13 years found that the health risks of alcohol vary by beverage type as well as quantity. Presented at the American College of Cardiology’s ACC.26 session, researchers reported that high alcohol intake was associated with worse outcomes across the board — 24% higher all‑cause mortality, 36% higher cancer mortality and 14% higher cardiovascular mortality compared with never or occasional drinkers. Differences emerged at low to moderate consumption: moderate wine drinkers had a 21% lower risk of dying from cardiovascular disease versus never/occasional drinkers, while even low intake of spirits, beer or cider was linked to a 9% higher cardiovascular death risk. Moderate consumption was defined as roughly 20–40g alcohol per day for men and 10–20g for women; high intake exceeded those ranges. Authors cautioned the findings are observational, may be influenced by lifestyle and socioeconomic confounders and rely on baseline self‑reporting; they suggested randomized trials and refined guidance are needed.