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Odyssey Therapeutics, a Boston-based biotech focused on autoimmune and inflammatory diseases, raised $279 million in an upsized U.S. initial public offering and began trading on the Nasdaq in early May 2026.
The company sold 15.5 million shares at $18 each; shares opened at $20 on debut, giving Odyssey a near-$900 million valuation, and initially rose about 11%. The offering was underwritten by J.P. Morgan, TD Cowen and Cantor.
Odyssey, founded by biotech veteran Dr.
Gary D. Glick, will use proceeds to advance its lead program OD‑001 (a RIPK2 inhibitor) through mid-stage ulcerative colitis trials and to fund other pipeline programs.
The IPO followed a concurrent private placement to a TPG affiliate and comes amid a broader pick-up in biotech equity activity in 2026 after a slow 2025, with other recent listings including Kailera and Alamar Biosciences.
Early trading showed some intraday volatility after the initial pop, reflecting investor caution around clinical-stage biotech valuations.
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🕰️ The Story So Far: An Evolving Timeline
Friday, May 8, 2026 18:42 UTC
Odyssey Therapeutics raises $279M in Nasdaq IPO
Tuesday, May 5, 2026 24:27 UTC
Odyssey Therapeutics targets $810 million US IPO


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