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Researchers at NASA’s Jet Propulsion Laboratory report that fungal spores recovered from spacecraft assembly cleanrooms can survive a suite of simulated space and Martian conditions, raising fresh concerns about forward contamination.
In experiments reported in Applied and Environmental Microbiology (April 2026), scientists collected 27 fungal strains from facilities used in the Mars 2020 program and exposed their asexual spores (conidia) to intense ultraviolet radiation, months-long ionizing radiation doses, low pressure, Mars-like regolith, and extreme cold.
Most strains survived UV exposure; one species, Aspergillus calidoustus, withstood UV, prolonged ionizing radiation and low-pressure, low-temperature conditions that mimic a mission to Mars.
Only prolonged exposure to a combination of very high radiation and extreme cold reliably killed it.
The team, led by Kasthuri Venkateswaran of JPL, says the findings do not prove Mars contamination will occur but highlight fungi as an underappreciated gap in planetary protection protocols.
The results also note potential human-health implications for astronaut safety and call for updated sterilisation and monitoring standards for future robotic and crewed missions.
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